The first pure phytoene for skincare

Phyt-N-Resist®, the first pure phytoene dedicated to cosmetic treatments

Phytoene is a colorless carotenoid obtained via a process of fermentation of natural sugars by the extremophilic bacterium Deinococcus geothermalis.

Created by DEINOVE and composed of phytoene concentrate in refined jojoba oil, Phyt-N-Resist® helps fight against aging skin by reducing oxidative stress and accelerating skin regeneration.

Its efficacy and safety have been successfully demonstrated by in vitro, ex vivo, and clinical studies.

Different dermo-cosmetic formulas have been developed, demonstrating ease of formulation and satisfactory stability. Due to the high temperature stability of this active ingredient, it is conceivable to also incorporate it into make-up formulas.

DEINOVE launched the marketing of this new active ingredient at the In-cosmetics Global 2018 trade show.



A breakthrough in naturally-sourced active ingredients: Deinove bioproduced the 1st pure Phytoene

Nature is a prodigious laboratory, capable of designing highly efficient molecules.

Both skin cells and plants rely on a common substance to protect themselves from oxidative stress: Phytoene, the original precursor of all carotenoids.  However, unlike plants, skin cannot synthesize it. Phytoene counts among these essential molecules that need to be brought through external supplementation.

So far there was no way to extract pure Phytoene. None of the available production processes from plants allows the production of pure Phytoene. They provide only a mix of carotenoids, at low concentration, and with varying degrees of stability and colors.  

Tapping into the extraordinary resources of biomimetism and symbiosis, harnessing the potential of Deinococcus geothermalis, a UV-resistant extremophile bacterium, Deinove has for the first time ever achieved the bioproduction of pure Phytoene.

Phyt-N-Resist®: Extended anti-ageing properties

Carotenoids are known for their anti-oxidant properties. Phyt-N-Resist® has been successfully tested for its ability to reduce the amount of lipoperoxidation products, appearing after cells exposure to UV radiations. Indeed, phytoene accumulates in cellular membranes to prevent cellular degradation. By protecting membranes lipids from free radicals and peroxidation, Phyt-N-Resist® reduces the harmful effects of oxidation and, ultimately, skin aging.

But Deinove went even further. The company has put in place a systematic screening of its active ingredients across several dimensions. This comprehensive, innovative approach has highlighted a previously untapped feature under the carotenoid family: cell renewal stimulation. Wounded skin is able to regenerate under the action of phytoene.

These properties were subsequently confirmed by a conclusive clinical study, demonstrating its beneficial effect on skin firmness, elasticity and radiance. Above all, Phyt-N-Resist® has a significant anti-wrinkles action.

This makes Phyt-N-Resist® a thorough anti-aging active ingredient for the beauty industry.

Key product features

  • Sharper approach to cell anti-oxidant protection
  • Clinically tested skin regeneration
  • Colorless & stable carotenoid
  • Consistent process and product quality
  • A concentrated ingredient, low incorporation rate
  • Easy to formulate
  • Advanced biotech science
  • Exclusive patented innovation
  • Ancient and highly resilient micro-organism surviving in extreme environments
  • Biomimetic solution
  • Supplementation of skin natural defenses
  • Made in France


INCI: Simmondsia chinensis (Jojoba) seed oil and C30-45 Olefin

China Compliant



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